Jackass star Johnny Knoxville and his wife Melanie are calling it quits on their twelve year marriage. "They have been separated," Knoxville's rep confirmed. Rumors of infidelity have dogged the couple for some time, including widespread speculation that Knoxville hooked up with Jessica Simpson while the pair were filming The Dukes of Hazzard. "How do you live knowing that your husband leads a separate life...and is sleeping with other women all the time?" said one source. "[Knoxville's wife] deserves every penny if she is going to divorce him." The former couple have a ten-year-old daughter, Madison.